Lithium ameliorates Cornelia de Lange syndrome associated phenotypes in experimental models
Paolo Grazioli, Chiara Parodi, Milena Mariani, Daniele Bottai, Elisabetta Di Fede, Aı́da Zulueta, Laura Avagliano, Anna Cereda, Romano Tenconi, Jolanta Wierzba, Raffaella Adami, Maria Rosaria Iascone, Paola Francesca Ajmone, Thomas Vaccari, Cristina Gervasini, , Valentina Massa
This study investigates the effects of lithium on CdLS phenotypes in experimental models, showing rescue of brain and behavioral abnormalities through WNT pathway activation.
bioRxiv · Jul 15, 2020 · PreprintGenetics