Cristina Gervasini

Drosophila SA1 expression prevents brain tumorigenesis and PARP-mediated cell elimination

The paper investigates the role of cohesin complex variants in brain tumorigenesis and shows that reduced cohesin activity increases apoptosis, which can be exploited through PARP inhibition.

Generation and benchmarking of a collection of hiPSC lines from Schizophrenia Patients with Diverse Clinical Profiles

The paper generates and validates a collection of hiPSC lines from Schizophrenia patients with diverse clinical profiles to model disease-specific neural phenotypes and develop targeted therapies.

Lithium ameliorates Cornelia de Lange syndrome associated phenotypes in experimental models

This study investigates the effects of lithium on CdLS phenotypes in experimental models, showing rescue of brain and behavioral abnormalities through WNT pathway activation.

Exogenous and endogenous HDAC inhibitor effects in Rubinstein-Taybi syndrome models

This study investigates the effects of HDAC inhibitors in RSTS models, showing molecular rescue and microbiota changes, and highlights the role of gut microbiota in chromatinopathy.