BioinformaticsCellular and Molecular Life SciencesPeer-reviewed
Functional Molecular Switches of Mammalian G Protein-Coupled Bitter-Taste Receptors
Jérémie Topin, Cédric Bouysset, Jody Pacalon…·Jérôme Golebiowski
The paper improves comparative modeling of mammalian bitter-taste receptors (TAS2Rs) by re-aligning sequences and constructing homology models, validated through site-directed mutagenesis and functional assays.
14 citations