Author

Xuexin Yu

Children's Hospital of PhiladelphiaORCID 0000-0002-7816-975XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hongyi ZhangiD· 2 shared Mingyao PaniD· 2 shared Yuhao TaniD· 2 shared Bo Li· 1 shared Bo LiiD· 1 shared Drew WeissmaniD· 1 shared Hailong HuiD· 1 shared Irina S. Shkundina· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Hongyi ZhangORCID

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2 papers

Recent·Most cited

Cancer cells hijack mitochondria from Bhlhe40+ T cells for immune evasion

Hailong Hu, Yuhao Tan, Irina S. Shkundina, Richard Madnick, Jing Hu, Hongyi Zhang, Ziqi Yang, Tong Wang, Xuexin Yu, Julia Fleming, Mingyao Pan, Yizhou Wang, Yuanyuan Pang, Drew Weissman, Bo Li

The paper identifies the Bhlhe40-S100a4 cascade as a key regulator of cancer cell mitochondrial transfer from T cells, offering a target for immunotherapy.

bioRxiv · Oct 28, 2026 · PreprintImmunology

MitoTracer facilitates the identification of informative mitochondrial mutations for precise lineage reconstruction

Xuexin Yu, Jing Hu, Yuhao Tan, Mingyao Pan, Hongyi Zhang, Bo Li

MitoTracer identifies informative mitochondrial mutations for lineage reconstruction from scRNA-seq and scATAC-seq data, showing high sensitivity and specificity.

PLoS Computational Biology · Jun 23, 2025Peer-reviewedBioinformatics