Author
Children's Hospital of PhiladelphiaORCID 0000-0002-8617-900XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Mingyao Pan, Yuhao Tan, Yizhou Tracy Wang, Jing Rong Hu, Julia Fleming, Hailong Hu, Ziqi Yang, Xiaowei Zhan, Bo Li
The paper introduces THNet, a method to analyze HLA-TCR cross-reactivity, revealing new disease associations and improving transplantation outcomes.
Science Advances · Oct 24, 2025Peer-reviewedBioinformatics
Xuexin Yu, Jing Hu, Yuhao Tan, Mingyao Pan, Hongyi Zhang, Bo Li
MitoTracer identifies informative mitochondrial mutations for lineage reconstruction from scRNA-seq and scATAC-seq data, showing high sensitivity and specificity.
PLoS Computational Biology · Jun 23, 2025Peer-reviewedBioinformatics
Jing Rong Hu, Mingyao Pan, Brett M. Reid, Shelley S. Tworoger, Bo Li
The paper identifies age-associated TCR repertoire components using a new computational framework and links them to immune aging and clinical outcomes.
Nature Communications · Sep 17, 2024Peer-reviewedImmunology
The paper identifies T cell receptor convergence as a marker of antigen-specific T cell responses in cancer immunotherapies, showing better predictive accuracy than existing TCR repertoire indexes.
eLife · Nov 9, 2022Peer-reviewedBioinformatics
Bo Li, Longchao Liu, Jian Zhang, Jiahui Chen, Jianfeng Ye, Alexander Filatenkov, Sachet Ashok Shukla, Jian Qiao, Xiaowei Zhan, Catherine J. Wu, Yang‐Xin Fu
The paper identifies cancer-associated T cells using TCR repertoire and gene expression data, revealing novel regulators and antigens with potential for immune monitoring and immunotherapy.
bioRxiv · Nov 1, 2018 · PreprintBioinformatics