Author

Michelle Darrieux

Universidade São FranciscoORCID 0000-0002-7829-3435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Lúcio Fábio Caldas FerraziD· 2 shared Thiago Rojas ConversoiD· 2 shared Anders HåkanssoniD· 1 shared Brenda Vieira Ferreira· 1 shared Bruna Terribile· 1 shared Carlos Augusto Real MartineziD· 1 shared Carlos Javier OrihuelaiD· 1 shared Gabriel Rodrigo· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Lúcio Fábio Caldas FerrazORCID

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2 papers

Recent·Most cited

Full title Capsule and PspA Cooperatively Confer Resistance of Streptococcus pneumoniae to the Human defensin HNP-1

Thalita Bastos de Freitas Silva, Maria Eduarda Pereira Mendes, Rebeca Faria, Kelvin Gattinoni, Bruna Terribile, Giulia Destro, Lúcio Fábio Caldas Ferraz, Carlos Javier Orihuela, Thiago Rojas Converso, Michelle Darrieux

This study shows that PspA and the polysaccharide capsule work together to protect Streptococcus pneumoniae from the antimicrobial peptide HNP-1.

bioRxiv · Sep 29, 2025 · PreprintMicrobiology

Protection Against Pneumonia Induced By Vaccination With Fimbriae Subunits From Klebsiella pneumoniae

Lucas Assoni, Isabelle Ciaparin, Monalisa Martins Trentini, Juliana Baboghlian, Gabriel Rodrigo, Brenda Vieira Ferreira, José Aires Pereira, Carlos Augusto Real Martinez, Lúcio Fábio Caldas Ferraz, Raquel Girardello, Lucas Miguel de Carvalho, Anders Håkansson, Thiago Rojas Converso, Michelle Darrieux

This study evaluates the protective potential of type 1 and 3 fimbriae subunits in a murine model of K. pneumoniae lung infection, showing reduced bacterial load and inflammation.

Vaccines · Mar 11, 2025Peer-reviewedImmunology