Shinichi Kawaguchi

This study shows that gut microbes influence germline stem cell proliferation in Drosophila by modulating metabolism, circadian genes, and hormonal signaling across tissues.

This study identifies Squash as a cofactor of Spindle-E that ensures heterotypic ping-pong piRNA amplification in Drosophila ovaries, preventing transposable element de-repression.

This study identifies stand still as a regulator of apoptosis in Drosophila female germline cells, revealing two mechanisms that suppress reaper transcription and prevent cell death.

The paper uses AlphaFold2 to predict protein interactions among nuage and piRNA-related proteins, validating several novel interactions through experimental methods.

This study identifies HemK2 as a methyltransferase that methylates eRF1, essential for protein synthesis and RNA stability during Drosophila oogenesis.

The paper identifies a mechanism by which endogenous protein-coding regions generate non-coding piRNAs in Drosophila testes, which are essential for spermatogenesis and gene regulation.