Hiroshi Mori

Akkermansia muciniphila-derived LPS links gut dysbiosis to pathogenic miR-21 signaling in experimental autoimmune encephalomyelitis.

This study identifies an A. muciniphila-LPS-miR-21 axis linking gut dysbiosis to neuroinflammation in MS by showing how gut microbiota modulate miRNA expression and CNS autoimmunity.

Microbe-dependent inter-organ communication regulates germline stem cell proliferation in Drosophila

This study shows that gut microbes influence germline stem cell proliferation in Drosophila by modulating metabolism, circadian genes, and hormonal signaling across tissues.

Diversity and stability of the gut microbiome of naked mole-rat (Heterocephalus glaber), the longest-lived rodent

This study characterizes the gut microbiome of naked mole-rats, revealing its stability across age and unique features associated with their low metabolic rate and longevity.

DFAST_QC: Quality Assessment and Taxonomic Identification Tool for Prokaryotic Genomes

DFAST_QC assesses prokaryotic genome quality and provides taxonomic classification, showing high consistency with NCBI taxonomy assignments.

Automated Harmonization and Large-Scale Integration of Heterogeneous Biomedical Sample Metadata Using Large Language Models

This paper introduces a framework using large language models to automate metadata harmonization and integration across biomedical studies, achieving higher recovery rates than traditional methods.

Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice

This study shows that Limosilactobacillus reuteri from tamely bred mice increases tameness and oxytocin levels when administered, suggesting a role in domestication.

Metagenomic thermometer

The paper develops a Metagenomic Thermometer to predict environmental temperature from metagenomic sequences, achieving high accuracy in hot spring samples and estimating human body temperature.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

This study shows DDX6 regulates early mouse embryogenesis by repressing negative BMP regulators via miRNA-mediated gene silencing, affecting cell lineage specification and germ layer development.

Neuroimaging within the Dominantly Inherited Alzheimer's Network (DIAN): PET and MRI

The paper describes MRI and PET protocols used in the DIAN study to investigate preclinical Alzheimer's disease and reports key imaging findings.

De novo virus inference and host prediction from metagenome using CRISPR spacers

The paper develops a CRISPR-based method to infer viral sequences and predict hosts from metagenomic data, identifying numerous viral genomes and analyzing the evolution of a retroelement locus.