Author

Michelle W. Ma

Harvard UniversityORCID 0000-0002-7834-2129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Cyrus Y. JiniD· 2 shared Eric J. BennettiD· 2 shared Eric S. FischeriD· 2 shared Julie K. MondaiD· 2 shared Moritz HunkeleriD· 2 shared Daan OverwijniD· 1 shared Katherine A. DonovaniD· 1 shared Marilyn Leonard· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Cyrus Y. JinORCID

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2 papers

Recent·Most cited

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

This study identifies HAPSTR1 as a HUWE1 substrate that facilitates its nuclear localization, thereby regulating stress signaling pathways and cell proliferation.

Cell Reports · May 1, 2023Peer-reviewedMolecular Biology

Modular HUWE1 architecture serves as hub for degradation of cell-fate decision factors

Moritz Hunkeler, Cyrus Y. Jin, Michelle W. Ma, Julie K. Monda, Daan Overwijn, Eric J. Bennett, Eric S. Fischer

The paper presents the cryo-EM structure of HUWE1, revealing its modular architecture and its role in degrading cell-fate decision factors.

Molecular Cell · Jul 26, 2021Peer-reviewedMolecular Biology