BiophysicsbioRxivPreprint
Engineering substrate selectivity in the human sodium/iodide symporter (NIS)
Alejandro Llorente-Esteban, Haswitha Sabbineni, Kendra Hoffsmith…·Nancy Carrasco
This paper engineers a sodium/iodide symporter variant that selectively transports oxyanions over iodide, enabling targeted cancer therapy without harming the thyroid.
DOI 10.1101/2025.10.07.681042