Nancy Carrasco

This paper engineers a sodium/iodide symporter variant that selectively transports oxyanions over iodide, enabling targeted cancer therapy without harming the thyroid.

This study shows overnutrition causes hypothyroidism in mice by impairing thyroid hormone biosynthesis and utilization, despite thyroid adaptations, and finds a link between BMI and thyroid vascularization in humans.

This study shows that inhibiting purine biosynthesis with mizoribine prevents weight gain and improves metabolic health in mice on a high-fat diet by increasing thermogenesis and reducing food intake.