Michael D. Henry

This study identifies PI3K-regulated TAZ/YAP and mTORC1 pathways in sarcomas and shows that targeting both synergistically reduces tumor growth.

This study shows that brief high-level fluid shear stress exposure enhances cancer cell invasiveness, metastatic potential, and metabolic adaptations that support survival in circulation.

This study identifies TFE3 and the non-canonical mTORC1 pathway as regulators of melanoma cell state plasticity, showing MITF suppresses the mesenchymal phenotype by modulating TFE3 expression.

This study investigates E-cadherin's role in 4T1 breast carcinoma metastasis, finding that E-cadherin is retained and does not determine metastatic capacity, with cells displaying hybrid epithelial/mesenchymal traits.