α2δ-2 mediates coupling of presynaptic calcium entry to vesicle release in hippocampal parvalbumin-expressing interneurons
Allison J. Ellingson, Emma Jerome, Ashlynn A. Gallagher, Eric Schnell
This study shows that α2δ-2 is essential for synaptic inhibition in hippocampal parvalbumin-expressing interneurons, with its absence leading to increased excitation and seizure-like activity.
bioRxiv · Sep 4, 2026 · PreprintNeuroscience