Jan Víteček

This paper designs next-generation thrombolytic proteases with improved catalytic efficiency, fibrin selectivity, and inhibition resistance through multi-objective enzyme engineering.

The paper compares biochemical and immunological properties of engineered low-immunogenic staphylokinase variants to identify the most promising for thrombolytic therapy.

This study compares the effects of gold and PEDOT electrodes on vascular endothelial cell function through electrostimulation, finding PEDOT enhances nitric oxide production and gene expression related to endothelial health.