Author

Sergey V. Nikulin

National Research University Higher School of EconomicsORCID 0000-0002-7900-5810Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrey A. PoloznikoviD· 2 shared A. A. Zakhariants· 1 shared A. V. RazumovskayaiD· 1 shared Abraham M. BrowniD· 1 shared Ben R. BrittiD· 1 shared Bindu Diana PauliD· 1 shared Bobby ThomasiD· 1 shared Dmitry M. HushpulianiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Andrey A. PoloznikovORCID

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Author profile →

2 papers

Recent·Most cited

FUNCTIONAL ANALYSIS OF BIPARTITE NRF2 ACTIVATORS THAT OVERCOME FEEDBACK REGULATION FOR AGE-RELATED CHRONIC DISEASES

Dmitry M. Hushpulian, Navneet Ammal Kaidery, Priyanka Soni, Andrey A. Poloznikov, A. A. Zakhariants, A. V. Razumovskaya, M. O. Silkina, Vladimir I. Tishkov, Eliot H. Kazakov, Abraham M. Brown, Irina N. Gaisina, Young‐Hoon Ahn, Sergey Viktorovich Kazakov, Nancy A. Krucher, Sudarshana M. Sharma, , Bobby Thomas

This paper identifies HPPE as a bipartite Nrf2 activator that overcomes feedback regulation by inhibiting Bach1, showing potential for treating age-related neurodegeneration.

Redox Biology · Jul 30, 2025Peer-reviewedBiochemistry

Advancing clinical outcome predictions via incorporating pharmacokinetic simulations into in vitro testing - a colorectal cancer example

Andrey A. Poloznikov, Ben R. Britt, Sergey V. Nikulin, Sergey Rodin, Karl‐Henrik Grinnemo, Martin Woywod, Jasmin Farouq

This study improves clinical outcome predictions by integrating pharmacokinetic simulations into in vitro testing for colorectal cancer, showing better classification of responders and non-responders than traditional methods.

bioRxiv · Jul 29, 2025 · PreprintPharmacology & Toxicology