Sergey Rodin

Single-cell proteomics of pancreatic islet cells reveals type 1 diabetes and donor-specific features

The paper performs single-cell proteomics on pancreatic islets from healthy and T1DM donors, identifying cell type-specific differences and donor-specific features.

Advancing clinical outcome predictions via incorporating pharmacokinetic simulations into in vitro testing - a colorectal cancer example

This study improves clinical outcome predictions by integrating pharmacokinetic simulations into in vitro testing for colorectal cancer, showing better classification of responders and non-responders than traditional methods.

Global analysis of protein turnover dynamics in single cells

This study introduces SC-pSILAC, a method to measure protein abundance and turnover in single cells, revealing differentiation-specific dynamics and cell-type markers in human iPSCs.

High-throughput and scalable single cell proteomics identifies over 5000 proteins per cell

This study improves single-cell proteomics by increasing protein identification from ~2000 to over 5000 per cell and enhancing throughput and reliability.

Testing the link between isoaspartate and Alzheimer's disease etiology

The paper investigates the link between isoaspartate (isoAsp) and Alzheimer's disease by analyzing isoAsp levels and related biomarkers in blood samples from AD patients and healthy controls.