BiochemistrybioRxivPreprint
Catalytic and Structural Insights into Neil3-Dependent Unhooking of Endogenous Abasic DNA Crosslink
Andrea Hušková, Barbora Landová, Viktoria Benova…·Jan Šilhán
This study clarifies the mechanism of NEIL3 in unhooking Ap-ICLs by showing that a processed form of NEIL3 efficiently removes crosslinks without generating strand breaks.
DOI 10.64898/2026.01.19.700286