Author

Niel M. Henriksen

Numerion Labs (United States)ORCID 0000-0002-7916-0757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Assmaa ElSheikhiD· 1 shared Camden M. DriggersiD· 1 shared Ha H. Truong· 1 shared John Allen· 1 shared Katarzyna Walczewska-SzewciD· 1 shared Show‐Ling ShyngiD· 1 shared Zhongying YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Assmaa ElSheikhORCID

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1 paper

Recent·Most cited

AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone

Assmaa ElSheikh, Camden M. Driggers, Ha H. Truong, Zhongying Yang, John Allen, Niel M. Henriksen, Katarzyna Walczewska-Szewc, Show‐Ling Shyng

The paper identifies a novel KATP channel pharmacochaperone, Aekatperone, using AI screening and cryoEM, showing reversible inhibition and functional recovery of trafficking mutants.

eLife · Mar 26, 2025Peer-reviewedBiochemistry