GeneticsbioRxivPreprint
Hijacking and recording intracellular RNAs in human cells using eukaryotic reprogrammed tracrRNAs
Seok-Hoon Lee, Junho Park, Chanju Jung, Sangsu Bae
The paper introduces CHEETAH, a system using reprogrammed tracrRNAs to capture and record intracellular RNAs in human cells, demonstrating its ability to self-edit, selectively record viral RNA fragments, and enable multiplexed, time-resolved recording.