Samantha Laber

This study identifies 12 enhancers in the 9p21.3 CAD risk locus that regulate MTAP, modulating vascular cell-state transitions and CAD risk through stress-responsive mechanisms.

This study identifies IRX3 as a regulator of sumoylation that controls adipogenesis and osteogenesis through epigenetic mechanisms, linking the FTO locus to obesity.

The paper introduces LipocyteProfiler, a high-throughput microscopy assay to profile lipid-storing cells and identifies cellular programs linked to metabolic traits like insulin resistance and lipodystrophy.

The paper develops a deep learning method for adipocyte phenotyping and finds adipocyte area correlates with BMI but no genome-wide significant genetic associations.

This study identifies genetic variants associated with sporadic and recurrent miscarriage through large-scale association analyses and Mendelian randomization.

This study finds that genetically or therapeutically lowering sclerostin increases cardiovascular risk, based on genetic variant analysis and clinical trial data.

A GWAS of erectile dysfunction identifies a new locus at 6q16.3, implicating hypothalamic neurobiology and diabetes in its etiology.

This study performs a GWAS meta-analysis of menstrual cycle length in European women, confirming the FSHB locus association and identifying four novel signals linked to the HPG axis.