Author

Laurence Lawrence‐Archer

Haukeland University Hospital

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Molecular Biology· 1

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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Gunnar MellgreniD· 1 shared Jan-Inge BjuneiD· 1 shared Kamal MustafaiD· 1 shared Melina ClaussnitzeriD· 1 shared Niyaz Al‐SharabiiD· 1 shared Pål R. NjølstadiD· 1 shared Patrizia Maria Christiane Nothnagel· 1 shared Pierre ChymkowitchiD· 1 shared

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1 shared paperMolecular Biology

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Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 6, 2025

Mechanisms of the FTO locus association with obesity: Irx3 controls a sumoylation-dependent switch between adipogenesis and osteogenesis

Jan-Inge Bjune, Samantha Laber, Laurence Lawrence‐Archer…·Simon N. Dankel

This study identifies IRX3 as a regulator of sumoylation that controls adipogenesis and osteogenesis through epigenetic mechanisms, linking the FTO locus to obesity.

7 citations

mouseATAC-seq

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