Author

C Chen

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:benchmark study· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Adam T. NelczykiD· 1 shared Amar Gopal ChittiboyinaiD· 1 shared Anasuya Das GuptaiD· 1 shared Baggio EvangelistaiD· 1 shared Benjamin M. NealeiD· 1 shared Betsy George· 1 shared Cecilia M. LindgreniD· 1 shared Claire P. SchaneiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Adam T. NelczykORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MICRON learns outcome-associated representations of spatial immune microenvironments

C Chen, Betsy George, Luvna Dhawka, Baggio Evangelista, Natalie Stanley

MICRON identifies outcome-linked immune microenvironments from spatial imaging proteomics data, improving prognostic and diagnostic prediction in brain cancer.

bioRxiv · Apr 16, 2026 · PreprintBioinformatics

Loss of Mast cells and histaminergic signaling link diet to platelet-mediated NETosis and mammary cancer recurrence

Claire P. Schane, Adam T. Nelczyk, C Chen, Jiyoung Seo, Yu Wang, Natalia Krawczyńska, Shruti V. Bendre, Erin Weisser, Dhanya Pradeep, Hashni Epa Vidana Gamage, Lara I. Kockaya, Y. Fei, Anasuya Das Gupta, Hannah Kim, Madeline A. Henn, , Erik Russell Nelson

This study links diet to mammary cancer recurrence via mast cell loss and histaminergic signaling, showing that H2R antagonists promote platelet-mediated NETosis and reemergence from dormancy.

bioRxiv · Apr 15, 2026 · PreprintCancer Biology

Lifelong genetically lowered sclerostin and risk of cardiovascular disease.

Jonas Bovijn, Kristi Krebs, C Chen, Ruth Boxall, Jenny C. Censin, Ticiane de Góes Mário Ferreira, Sara L. Pulit, Craig A. Glastonbury, Samantha Laber, Iona Y. Millwood, Kuang Lin, Liming Li, Zhengming Chen, Lili A. Milani, Robin G. Walters, , Michael Vaclav Holmes

This study finds that genetically or therapeutically lowering sclerostin increases cardiovascular risk, based on genetic variant analysis and clinical trial data.

bioRxiv · Feb 1, 2019 · PreprintGenetics