Gregory I. Lang

The paper examines regulatory divergence in Saccharomyces yeasts and finds that while cis and trans regulatory effects are widespread, hybrid gene expression remains largely conserved due to compensatory divergence.

The paper quantifies dominant and recessive mutation rates in yeast mating pathway mutants and identifies genes associated with dominance.

This study shows that weak genetic incompatibilities, rather than strong pairwise ones, drive adaptation in hybrid yeast genomes through background-dependent interactions and mutational targeting.

The paper introduces a method called cytoduction to efficiently transfer plasmids into diverse yeast libraries while preserving genetic diversity.