The vitellogenesis pathway of the tick host Ixodes scapularis regulates Rickettsia buchneri transcriptional state and persistence
Dattatray V. Sawant, Yating Dong, Haritha Katasani, Jonathan D. Oliver, Benjamin Cull, Benedict S. Khoo, Michel Shamoon‐Pour, Amanda Baliban, Jianmin Zhong, Saravanan Thangamani, Ulrike G. Munderloh, Timothy J. Kurtti, Xin-Ru Wang
This study shows that the tick's vitellogenesis pathway regulates the transcriptional state of its endosymbiont Rickettsia buchneri, independent of bacterial abundance.
bioRxiv · Aug 6, 2026 · PreprintMicrobiology