Author

Benedict S. Khoo

Nationwide Children's HospitalORCID 0000-0003-0222-7228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amanda Baliban· 1 shared Benjamin CulliD· 1 shared Dattatray V. Sawant· 1 shared Haritha KatasaniiD· 1 shared Jianmin ZhongiD· 1 shared Jonathan D. OliveriD· 1 shared K. John McLaughlin· 1 shared Mehmet Emir YALVAÇiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Amanda Baliban

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 6, 2026

The vitellogenesis pathway of the tick host Ixodes scapularis regulates Rickettsia buchneri transcriptional state and persistence

Dattatray V. Sawant, Yating Dong, Haritha Katasani…·Xin-Ru Wang

This study shows that the tick's vitellogenesis pathway regulates the transcriptional state of its endosymbiont Rickettsia buchneri, independent of bacterial abundance.

DOI 10.64898/2026.08.06.743197

mouseproteomics

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Molecular BiologyFrontiers in GeneticsPeer-reviewedApr 6, 2021

Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome

Syed-Rehan A. Hussain, Mehmet Emir YALVAÇ, Benedict S. Khoo…·K. John McLaughlin

This study demonstrates a method to edit mitochondrial DNA using CRISPR-Cas9 by modifying guide RNA with a stem loop element for mitochondrial targeting.

102 citationstop 2%

humanCRISPR screen

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