Yu Luo

Ablation of the choroid plexus attenuates hydrocephalus induced parenchymal edema but moderately reduces postnatal hippocampal neurogenesis

This study investigates the effects of choroid plexus ablation on hydrocephalus and neurogenesis, finding that it reduces parenchymal edema but only moderately affects hippocampal neurogenesis.

Microglia-derived TGF-β1 ligand maintains microglia homeostasis via autocrine mechanism and is critical for normal cognitive function in adult mouse brain

This study identifies microglia as the primary source of TGF-β1 ligand in the adult mouse brain, showing its role in maintaining microglial homeostasis and cognitive function through an autocrine mechanism.

The choroid plexus maintains ventricle volume and adult subventricular zone neuroblast pool, which facilitates post-stroke neurogenesis

This study uses a genetic mouse model to show that choroid plexus ablation reduces subventricular zone neuroblasts and impairs post-stroke neurogenesis.

Finding the right tool: a comprehensive evaluation of microglial inducible cre mouse models

This study evaluates four microglial CreER mouse models to compare their recombination specificity, leakiness, efficiency, extra-neural recombination, and off-target effects in neonatal brain development and injury models.

Mapping the corticoreticular pathway from cortex-wide anterograde axonal tracing in the mouse

This study maps the corticoreticular pathway in mice, showing its widespread cortical origins and strong bilateral projections compared to the corticospinal tract.