Author

Gabriel L. McKinsey

University of California, San FranciscoORCID 0000-0002-5503-2830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Thomas D. ArnoldiD· 3 shared Richard DanemaniD· 2 shared Aaron J. LongworthiD· 1 shared Aditya KatewaiD· 1 shared Agnieszka CiesielskaiD· 1 shared Alex S. NordiD· 1 shared Alexander Z Zhang· 1 shared Alicia BedollaiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Thomas D. ArnoldORCID

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Author profile →

4 papers

Recent·Most cited

Dynamic fibroblast-immune interactions shape wound healing after brain injury

Nathan A. Ewing-Crystal, Nicholas M. Mroz, Amara Larpthaveesarp, Carlos O. Lizama, Remy Pennington, Pailin Chiaranunt, Jason I. Dennis, Anthony A. Chang, Eric Dean Merrill, Sofia E. Caryotakis, Nikhita Kirthivasan, Leon Teo, Tatsuya Tsukui, Aditya Katewa, Gabriel L. McKinsey, , Ari B. Molofsky

This study identifies dynamic fibroblast-immune interactions that regulate CNS wound healing and neuroinflammation after brain injury.

Nature · Sep 3, 2025Peer-reviewedImmunology

Microglia are not required for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

Caterina P. Profaci, Sean S. Harvey, Kaja Bajc, Tony Z Zhang, Danielle A Jeffrey, Alexander Z Zhang, Kelsey Marie Nemec, Hayk Davtyan, Carleigh A. O’Brien, Gabriel L. McKinsey, Aaron J. Longworth, Timothy P McMullen, Joia Kai Capocchi, Jessica G Gonzalez, Devon A. Lawson, , Richard Daneman

The paper investigates the role of microglia in maintaining blood-brain barrier properties in health and finds that microglia are not required, but PLX5622 treatment affects endothelial cholesterol metabolism.

Neuron · Aug 13, 2024Peer-reviewedNeuroscience

Finding the right tool: a comprehensive evaluation of microglial inducible cre mouse models

Alicia Bedolla, Gabriel L. McKinsey, Kierra Ware, Nicolas G. Santander, Thomas D. Arnold, Yu Luo

This study evaluates four microglial CreER mouse models to compare their recombination specificity, leakiness, efficiency, extra-neural recombination, and off-target effects in neonatal brain development and injury models.

Cell Reports · Jan 1, 2024Peer-reviewedNeuroscience

Single Cell Enhancer Activity Maps Neuronal Lineages in Embryonic Mouse Basal Ganglia

Linda Su-Feher, Anna Noren Rubin, Shanni N. Silberberg, Rinaldo Catta-Preta, Kenneth J. Lim, Iva Zdilar, Christopher S. McGinnis, Gabriel L. McKinsey, Thomas E. Rubino, Michael Hawrylycz, Carol L. Thompson, Zev J. Gartner, Luis Puelles, Hongkui Zeng, John L.R. Rubenstein, Alex S. Nord

The paper uses scRNA-seq and enhancer-based labeling to map neuronal lineages in embryonic mouse basal ganglia and identifies novel lineage specification paths.

bioRxiv · Jan 11, 2021 · PreprintNeuroscience