Laura M. J. Fernandez

The paper identifies a conserved locus coeruleus (LC) fMRI signature across sleep, anesthesia, and wakefulness, showing its impact on brain-state transitions and functional connectivity.

The paper shows that vagal afferent activation induces brain-body cooling and NREM-sleep-like states while increasing locus coeruleus activity.

This study shows that LC activity partitions NREM sleep into brain and autonomic states that regulate the NREM-REM cycle, with high activity enabling microarousals and low activity required for REMS entries.

This study shows that autophagy in parvalbumin interneurons is essential for synaptic proteostasis, inhibitory transmission, and memory, but not for Purkinje cells.

The paper analyzes REM sleep activity in mice using experimental data and a computational model, finding SWA is prominent in somatosensory areas and linked to reduced cortical responsiveness.

The paper shows that noradrenaline fluctuations during non-REM sleep influence sleep spindle clustering and heart rate variations through thalamic circuits.

This study identifies a thalamic reticular circuit that integrates sensory cues with internal head-direction signals to regulate spatial navigation strategies.