Author

Ahmed Khalaf

University of NottinghamORCID 0000-0002-7945-398XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alessandro RettinoiD· 1 shared Alexander J. GarviniD· 1 shared David M. HeeryiD· 1 shared Jérôme Xicluna· 1 shared Joanna R. MorrisiD· 1 shared Laura Butler· 1 shared Nicole M ClarkeiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Alessandro RettinoORCID

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1 paper

Recent·Most cited

GSK3β-SCF-FBXW7 mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover.

Alexander J. Garvin, Ahmed Khalaf, Alessandro Rettino, Jérôme Xicluna, Laura Butler, Joanna R. Morris, David M. Heery, Nicole M Clarke

This paper identifies GSK3β-mediated phosphorylation of IRF1 at T181, which promotes its ubiquitination and degradation, essential for its transcriptional activity and anti-proliferative function.

Nucleic Acids Research · Mar 7, 2019Peer-reviewedMolecular Biology