Christopher E. Carr

Anaerobic methane oxidation by ANME-2a at 2 M chloride in the Orca Basin halocline

The paper investigates anaerobic methane oxidation in the Orca Basin, identifying ANME-2a's role at high salinity and revealing microbial communities involved in methane cycling.

Validation of Gentamicin and Streptomycin Stability for On-Orbit Microbial Monitoring

This study validates the stability of gentamicin and streptomycin in agar plates over 6.5 months at 4°C, finding slight degradation but overall stability suitable for the GEARS project.

Overcoming nucleotide bias in the nonenzymatic copying of RNA templates.

This study demonstrates a method to overcome nucleotide bias in nonenzymatic RNA copying using a prebiotically plausible mixture of nucleotides and oligonucleotides.

Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension

The paper investigates error frequency in nonenzymatic RNA primer extension by analyzing sequence context and the competition between bridged dinucleotides and mononucleotides.

Nanopore Sequencing at Mars, Europa and Microgravity Conditions

This study demonstrates nanopore sequencing functionality under reduced gravity conditions relevant to space exploration, including Mars and icy moons, showing consistent performance across different gravitational environments.

Deep sequencing of nonenzymatic RNA primer extension

The paper introduces a deep-sequencing methodology to study nonenzymatic RNA primer extension and demonstrates its effectiveness in analyzing sequence access and fidelity.

Nucleic acid extraction and sequencing from low-biomass synthetic Mars analog soils for in situ life detection

This study validates nucleic acid extraction and low-input nanopore sequencing from Mars analog soils to detect genetic sequences indicative of potential life on Mars.

CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing

CarrierSeq identifies low-input target reads from nanopore sequencing by filtering out contamination and noise using a statistical test based on channel-specific read patterns.