Author

Mark J. Brown

Claremont BioSolutions (United States)ORCID 0000-0002-3874-1352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Assay:imaging· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alex CraneiD· 1 shared Allison L. KuipersiD· 1 shared Andrew A. Wendling· 1 shared Angel MojarroiD· 1 shared Christopher E. CarriD· 1 shared Claire C. ChuiD· 1 shared Cynthia St. HilaireiD· 1 shared Gary RuvkuniD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

Alex CraneORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rapamycin Reduces Arterial Mineral Density and Promotes Beneficial Vascular Remodeling in a Murine Model of Severe Medial Arterial Calcification

Parya Behzadi, Andrew A. Wendling, Rolando A. Cuevas, Alex Crane, Claire C. Chu, William J. Moorhead, Ryan Wong, Mark J. Brown, Joshua Tamakloe, Swathi Suresh, Payam Salehi, Iris Zamir Jaffe, Allison L. Kuipers, Lyudmila Lukashova, Konstantinos Verdelis, Cynthia St. Hilaire

This study shows rapamycin reduces arterial mineral density and improves vascular structure in Mgp-/- mice with medial arterial calcification, though calcification volume remains unchanged.

American Journal of Physiology-Heart and Circulatory Physiology · May 8, 2025Peer-reviewedPhysiology

Nucleic acid extraction and sequencing from low-biomass synthetic Mars analog soils for in situ life detection

Angel Mojarro, Julie Hachey, Ryan Bailey, Mark J. Brown, Robert W. Doebler, Gary Ruvkun, Maria T. Zuber, Christopher E. Carr

This study validates nucleic acid extraction and low-input nanopore sequencing from Mars analog soils to detect genetic sequences indicative of potential life on Mars.

Astrobiology · Jun 17, 2019Peer-reviewedMolecular Biology

An evidence-based approach to globally assess the covariate-dependent effect of MTHFR SNP rs1801133 on plasma homocysteine: a systematic review and meta-analysis

Huifeng Jin, Haojie Cheng, Wei Chen, Xiaoming Sheng, Mark A. Levy, Mark J. Brown, Junqiang J. Tian

This paper assesses how the MTHFR SNP rs1801133 affects plasma homocysteine levels, considering covariates like folic acid intake, and finds significant variability due to effect modification and confounding.

American Journal of Clinical Nutrition · Feb 12, 2018Peer-reviewedGenetics