Andre Tesainer Brunetto

This study identifies CRTC1 as a marker of transcriptional heterogeneity in Group 3 β medulloblastoma, linking its expression to survival and tumor microenvironment features.

This study identifies high PSEN1 expression as a favorable-prognosis state in SHH medulloblastoma, associated with a distinct transcriptional program.

The paper shows that K252a treatment delays Ewing sarcoma tumor growth and reduces Trk, PI3K, and IGF1R expression and activity, with combined treatment more effective than single agents.

This study shows that valproic acid reduces medulloblastoma cell viability and affects stemness, differentiation, and gene expression through histone acetylation changes.