Marcelo A. C. Fernandes

The paper shows that K252a treatment delays Ewing sarcoma tumor growth and reduces Trk, PI3K, and IGF1R expression and activity, with combined treatment more effective than single agents.

The paper examines TWIST1 expression in medulloblastoma subgroups, finding opposite associations with patient survival in SHH and Group 4 tumors.

This study shows that valproic acid reduces medulloblastoma cell viability and affects stemness, differentiation, and gene expression through histone acetylation changes.

This paper applies stacked sparse autoencoders to classify SARS-CoV-2 genomes using k-mer image representations, achieving good performance in taxonomic classification.

This paper presents a parallel FPGA implementation of the Smith-Waterman algorithm to accelerate sequence alignment by optimizing the Forward and Backtracking steps.