Author

James L. Warner

Harvard UniversityORCID 0000-0002-7960-7360Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Fred WinstoniD· 2 shared Václav VeverkaiD· 2 shared Vanda LuxiD· 2 shared Alexandra R. ElchertiD· 1 shared Tereza NesporovaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersMolecular Biology

Fred WinstonORCID

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2 papers

Recent·Most cited

Regulation of the histone H3K36 methyltransferase Set2 by the histone chaperone Spt6

Alexandra R. Elchert, Vanda Lux, James L. Warner, Tereza Nesporova, Václav Veverka, Fred Winston

This study investigates how the histone chaperone Spt6 regulates the H3K36 methyltransferase Set2 by relieving its autoinhibition, impacting transcription and H3K36 methylation.

Nucleic Acids Research · Aug 14, 2026Peer-reviewedMolecular Biology

The histone chaperone Spt6 controls chromatin structure through its conserved N-terminal domain

James L. Warner, Vanda Lux, Václav Veverka, Fred Winston

This paper shows that the Spt6 N-terminal domain binds histones and controls chromatin structure, with its function conserved between yeast and humans.

Molecular Cell · Sep 1, 2025Peer-reviewedMolecular Biology