Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes
Stefan Schattgen, Kasi Vegesana, William D. Hazelton, Anastasia A. Minervina, Sebastiaan Valkiers, Kamil Slowikowski, Neal Patrick Smith, MGH COVID-19 Team, Alexandra–Chloé Villani, Paul Glyndwr Thomas, Philip H Bradley
The paper analyzes 6 million T cells from 91 studies to identify TCR sequence convergence patterns and their association with functional and cellular T cell phenotypes.
bioRxiv · May 31, 2025 · PreprintImmunology