Author

Stefan Schattgen

St. Jude Children's Research HospitalORCID 0000-0002-6860-5079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Paul Glyndwr ThomasiD· 3 shared Aaron C. LiuiD· 2 shared Alexander V. ChervonskyiD· 2 shared Alexandra CassanoiD· 2 shared Alia Welsh· 2 shared Ananda W. GoldrathiD· 2 shared Andrea Lebron Figueroa· 2 shared Anna-Maria GlobigiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Paul Glyndwr ThomasORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity

Nikolaj Pagh Kristensen, Thanos Tsaktanis, Sina Frischholz, Jasim Kada Benotmane, Lucia Klotz, Philipp Hilgendorf, M. Grotz, Mariana Sousa, Lasse Frank Voss, Stefan Schattgen, Vanessa Lang, Hannah Reimann, Cosima Storr, Roland Lang, Bernd M. Spriewald, , Kilian Schober

The paper identifies an EBV-specific T cell program in MS patients that contributes to CNS autoimmunity through B cell and myeloid cell activation.

bioRxiv · Oct 1, 2026 · PreprintImmunology

Genomic Specificity of Anti-TCR mAbs determined by single-cell RNAseq

Ian Magill, Val Piekarsa, Σοφία Κοσσίδα, Joshua D. Croteau, Amy Huei‐Yi Lee, ROBERT S. BALDERAS, David Zemmour, Christophe O. Benoist, immgenT Project, Aaron C. Liu, Alexander V. Chervonsky, Alexandra Cassano, Alia Welsh, Ananda W. Goldrath, Andrea Lebron Figueroa, , Xutong Gong

The paper identifies TCR-V gene usage patterns in T cells sorted by anti-TCR mAbs using single-cell RNAseq and finds enriched ERV1-family LTR expression in specific TRBV regions.

The Journal of Immunology · Aug 1, 2025Peer-reviewedImmunology

Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Abigail A. Jaquish, Eleni Phung, Xutong Gong, Pilar Baldominos, Silvia Galván-Peña, Ian Magill, Isabelle Bursulaya, Eleonora Marina, Aaron C. Liu, Alexander V. Chervonsky, Alexandra Cassano, Alia Welsh, Ananda W. Goldrath, Andrea Lebron Figueroa, Ankit Malik, , Deepshika Ramanan

The paper examines T cell changes in mammary glands during pregnancy and lactation, finding an expansion of T effector cells and similarities to intestinal T cells.

Nature Immunology · Jul 29, 2025Peer-reviewedImmunology

Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes

Stefan Schattgen, Kasi Vegesana, William D. Hazelton, Anastasia A. Minervina, Sebastiaan Valkiers, Kamil Slowikowski, Neal Patrick Smith, MGH COVID-19 Team, Alexandra–Chloé Villani, Paul Glyndwr Thomas, Philip H Bradley

The paper analyzes 6 million T cells from 91 studies to identify TCR sequence convergence patterns and their association with functional and cellular T cell phenotypes.

bioRxiv · May 31, 2025 · PreprintImmunology