Author

Ceylan Verda Bitirim

Ankara UniversityORCID 0000-0002-7979-0679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dunya AydosiD· 2 shared Zeynep Büşra AksoyiD· 2 shared Belma TuraniD· 1 shared Erdinç SezginiD· 1 shared Kamil Can AkçalıiD· 1 shared Kardelen GenciD· 1 shared Mehmet Altay ÜnaliD· 1 shared Neslihan Basak· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Dunya AydosORCID

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2 papers

Recent·Most cited

Pretreatment with estrogen enhances the therapeutic efficacy of cardiac progenitor cells and improves cardiac recovery in a failing heart model

Dunya Aydos, Neslihan Basak, Yusuf Olğar, Kardelen Genc, Recep Uyar, Okan Ekim, Taras Sych, Zeynep Büşra Aksoy, Tugba Aktan Kosker, Erdinç Sezgin, Ceylan Verda Bitirim

This study shows that estrogen pretreatment of cardiac progenitor cells improves their engraftment and therapeutic efficacy in a failing heart model, enhancing cardiac recovery and reducing pathological remodeling.

bioRxiv · Jun 25, 2025 · PreprintMolecular Biology

Dual GLP-1 and GIP receptor agonist Tirzapetide plays an off-target role in the modulation of the β-adrenoceptors and glucose metabolism in hyperglycemic or senescent cardiac cells

Dunya Aydos, Zeynep Büşra Aksoy, Mehmet Altay Ünal, Kamil Can Akçalı, Ceylan Verda Bitirim, Belma Turan

This study investigates how Tirzapetide modulates β-adrenoceptors and glucose metabolism in cardiac cells under hyperglycemic or senescent conditions, revealing off-target effects beyond its primary GLP-1 and GIP receptor agonism.

bioRxiv · Apr 9, 2025 · PreprintMolecular Biology