Author

Josephine Mun Yee Ko

University of Hong KongORCID 0000-0002-7997-331XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Maria Li LungiD· 2 shared Alvin Ka-Kiu Leung· 1 shared An‐Yi Xu· 1 shared Anthony W.I. LoiD· 1 shared Biaohua WuiD· 1 shared Bryan Chee-chad Lung· 1 shared Carissa Wing-Yan WongiD· 1 shared Cheryl Chee Heng Lung· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Maria Li LungORCID

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2 papers

Recent·Most cited

Disrupting Myeloid Persistence and Replenishment Enables Sustained Control of Esophageal Squamous Cell Carcinoma

Bryan Chee-chad Lung, Alvin Ka-Kiu Leung, Songran Liu, Carissa Wing-Yan Wong, Tsz Hong Lai, Yhi Wong, Cheryl Chee Heng Lung, Anthony W.I. Lo, Ngar‐Woon Kam, Josephine Mun Yee Ko, Wei Dai, Dora Lai‐Wan Kwong, Simon Law, Pablo Scodeller, Maria Li Lung, Valen Zhuoyou Yu

The paper shows that combining CSF1R inhibition with low-dose decitabine suppresses both myeloid persistence and replenishment, leading to sustained control of ESCC in multiple models.

bioRxiv · Aug 28, 2026 · PreprintCancer Biology

Large-Scale Whole-Exome Sequencing Association Study Implicates Genetic Effects on Viral Oncogenesis and Tumor Microenvironment in Nasopharyngeal Carcinoma

Yanni Zeng, Chun-Ling Luo, Guo‐Wang Lin, Fugui Li, Xiaomeng Bai, Josephine Mun Yee Ko, Lei Xiong, Yang Liu, Shuai He, Jiaxin Jiang, Wenxin Yan, Enya H.W. Ong, Zheng Li, Ya-Qing Zhou, Yun-He Zhou, , Jin‐Xin Bei

This study identifies three novel germline variants associated with nasopharyngeal carcinoma risk and introduces a refined polygenic risk score linked to EBV infection.

Journal of Clinical Investigation · Jan 1, 2025Peer-reviewedGenetic & Genomic Medicine