BioinformaticsBriefings in BioinformaticsPeer-reviewed
Enhanced compound-protein binding affinity prediction by representing protein multimodal information via a coevolutionary strategy
Binjie Guo, Hanyu Zheng, Haohan Jiang…·Xuhua Wang
This paper introduces FeatNN, a coevolutionary strategy for predicting compound-protein binding affinity by jointly representing protein sequence and structure information, achieving higher accuracy than existing methods.