Author

John D. Watt

Los Alamos National LaboratoryORCID 0000-0002-8012-9837Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Achraf NoureddineiD· 1 shared Alexander S. HalliD· 1 shared Benjamin R MarwedeliD· 1 shared C.Y. DangiD· 1 shared Carmine Schiavone· 1 shared Christina R. SteadmaniD· 1 shared Cullen RothiD· 1 shared Isaac Huber· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Achraf NoureddineORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

AI-Assisted Cryo-ET Workflow for 3D Visualization of Chromatin during Cellular Differentiation

John D. Watt, Cullen Roth, Isaac Huber, Alexander S. Hall, Manish Kumar Singh, Sofiya Micheva‐Viteva, Karissa Y. Sanbonmatsu, Shawn R. Starkenburg, Christina R. Steadman

This paper presents an AI-assisted cryo-ET workflow to visualize chromatin compaction during motor neuron differentiation and correlates findings with Hi-C data.

Biochemistry and Biophysics Reports · Sep 11, 2026Peer-reviewedGenomics

Rational Design of Immunogenic Nanoparticles as a Platform for Enhanced Ovarian Cancer Immunotherapy in Mice

Lien Tang, Benjamin R Marwedel, C.Y. Dang, Marian Olewine, Melanie S. Jun, Paulina M. Naydenkov, Lorél Y. Medina, Veronica Gayoso, Ngoc Doan, Shamus L O'Leary, Carmine Schiavone, Joseph Cave, Tamara A. Howard, John D. Watt, Prashant Dogra, , Achraf Noureddine

This paper designs immunogenic nanoparticles to enhance ovarian cancer immunotherapy in mice by co-loading multiple therapeutic agents and adjuvants, showing improved survival and immune activation.

bioRxiv · Jun 5, 2025 · PreprintImmunology