Rational Design of Immunogenic Nanoparticles as a Platform for Enhanced Ovarian Cancer Immunotherapy in Mice
Lien Tang, Benjamin R Marwedel, C.Y. Dang, Marian Olewine, Melanie S. Jun, Paulina M. Naydenkov, Lorél Y. Medina, Veronica Gayoso, Ngoc Doan, Shamus L O'Leary, Carmine Schiavone, Joseph Cave, Tamara A. Howard, John D. Watt, Prashant Dogra, , Achraf Noureddine
This paper designs immunogenic nanoparticles to enhance ovarian cancer immunotherapy in mice by co-loading multiple therapeutic agents and adjuvants, showing improved survival and immune activation.
bioRxiv · Jun 5, 2025 · PreprintImmunology