Author

Åsa Maria Wheelock

Karolinska University HospitalORCID 0000-0002-8013-2745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetic & Genomic Medicine· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:human· 3 Research Focus:benchmarking· 2 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Iryna KolosenkoiD· 4 shared Ákos VégváriiD· 2 shared Benedikt ZöhreriD· 2 shared Martina BonattiiD· 2 shared Nicole Wagner· 2 shared Pia LindbergiD· 2 shared Anders EklúndiD· 1 shared Antje PrasseiD· 1 shared

Activity by Year

2024-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBioinformatics

Iryna KolosenkoORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unraveling genetic mysteries: phenotype-shaping profiles in chronic sarcoidosis

Susanna Kullberg, Pernilla Darlington, David Ellinghaus, Antje Prasse, Tomoko Iseda, Olga D. Chuquimia, Anders Eklúnd, S Schreiber, Joachim Müller-Quernheim, Ingrid Skelton Kockum, Åsa Maria Wheelock, Leonid Padyukov, Mehdi Seyed Mirsaeidi, Paolo Spagnolo, Natalia V. Rivera

The paper identifies genetic variants associated with chronic sarcoidosis phenotypes using genome-wide association studies and functional analysis.

medRxiv · Dec 29, 2024 · PreprintGenetic & Genomic Medicine

Characterization of HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls

Benedikt Zöhrer, Ákos Végvári, Martina Bonatti, Iryna Kolosenko, Nicole Wagner, Antonio Checa, Vijay Joshua, Carl Magnus Sköld, Karin Lundberg, Lars Klareskog, Vivianne Malmström, Åsa Maria Wheelock

This study characterizes the HLA-DR immunopeptidome in lung cells of early RA patients and healthy smokers, finding that HLA-DR genotype drives the immunopeptidome more than RA status or sex.

bioRxiv · Dec 2, 2024 · PreprintImmunology

Multi-modal microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveal presence from extracellular vesicles

Martina Bonatti, Monika Ezerskyte, P. Lindberg, Benedikt Zöhrer, Iryna Kolosenko, Ákos Végvári, Åsa Maria Wheelock

This study analyzes miRNAs and proteins in exhaled particles to explore their role in respiratory diseases using non-invasive PExA sampling.

bioRxiv · Nov 12, 2024 · PreprintPhysiology

CORACLE (COVID-19 liteRAture CompiLEr): A platform for efficient tracking and extraction of SARS-CoV-2 and COVID-19 literature, with examples from post-COVID with respiratory involvement

Kristina Piontkovskaya, Yulian Luo, Pia Lindberg, Jing Gao, Michael Runold, Iryna Kolosenko, Chuanxing Li, Åsa Maria Wheelock

CORACLE is a web tool for tracking and analyzing COVID-19 literature, enabling users to explore publication networks and MeSH terms to identify key research trends and publications.

Computational and Structural Biotechnology Journal · Jun 20, 2024Peer-reviewedBioinformatics

Enhancing the Robustness of OPLS Modelling in Small Cohorts by Leveraging Permutation Analysis Prior to Variable Selection

Marika Ström, Nicole Wagner, Iryna Kolosenko, Åsa Maria Wheelock

This paper introduces a permutation-based approach to improve OPLS model robustness in small cohorts by adjusting Q2 values and using variable selection with Elastic Net.

bioRxiv · Mar 18, 2024 · PreprintBioinformatics