Author

Carolyne Horner

British Society for Antimicrobial ChemotherapyORCID 0000-0002-8026-3024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Julian ParkhilliD· 3 shared Sharon J. PeacockiD· 3 shared Beth BlaneiD· 2 shared David M. AanenseniD· 2 shared Nicholas M. BrowniD· 2 shared Alan McNallyiD· 1 shared Catherine LuddeniD· 1 shared Christopher Connor· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBioinformatics

Julian ParkhillORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 4, 2019

Contrasting approaches to genome-wide association studies impact the detection of resistance mechanisms in Staphylococcus aureus

Nicole E. Wheeler, Sandra Reuter, Claire Chewapreecha…·Sharon J. Peacock

The paper evaluates GWAS methods for detecting antibiotic resistance in Staphylococcus aureus genomes, finding they identify novel resistance mutations but are less accurate than literature-based approaches.

7 citations

bacteria (other)whole-genome sequencing

𝕏 PostBluesky

GenomicsmBioPeer-reviewedJan 21, 2019

One Health genomic surveillance of Escherichia coli demonstrates distinct lineages and mobile genetic elements in isolates from humans versus livestock

Catherine Ludden, Kathy E. Raven, Dorota M. Jamrozy…·Sharon J. Peacock

The paper compares E. coli isolates from humans and livestock to assess transmission and resistance gene sharing, finding genetic distinctions and limited shared antimicrobial resistance genes.

222 citationstop 1%

E. coliwhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivPreprintNov 29, 2018

Signatures of negative frequency dependent selection in colonisation factors and the evolution of a multi-drug resistant lineage of Escherichia coli

Alan McNally, Teemu Kallonen, Christopher Connor…·Jukka Corander

This study identifies negative frequency-dependent selection in Escherichia coli ST131 as a key driver of its evolutionary success and adaptation to different ecological niches.

DOI 10.1101/400374

E. coliwhole-genome sequencing

𝕏 PostBluesky