Author

Celso M. Teixeira‐Duarte

Howard Hughes Medical InstituteORCID 0000-0002-8036-7069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jianghuang WangiD· 1 shared Qing ZhongiD· 1 shared Wan FuiD· 1 shared Weizhong ZengiD· 1 shared Xinzhe JiangiD· 1 shared Youxing JiangiD· 1 shared Ziye Zhao· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Jianghuang WangORCID

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1 paper

Recent·Most cited

Structural mechanism of Necrocide 1 activation of human TRPM4 that triggers necrosis by sodium overload

Celso M. Teixeira‐Duarte, Wan Fu, Weizhong Zeng, Jianghuang Wang, Xinzhe Jiang, Ziye Zhao, Qing Zhong, Youxing Jiang

This study identifies the molecular mechanism of Necrocide 1 activation of human TRPM4 and explains its species-specific selectivity using cryo-EM, electrophysiology, and cell death assays.

Nature Communications · Jun 24, 2026Peer-reviewedBiophysics