Molecular BiologybioRxivPreprint
HDL regulates TGFβ-receptor lipid raft partitioning, restoring contractile features of cholesterol-loaded vascular smooth muscle cells
Prashanth Thevkar Nagesh, Hitoo Nishi, Shruti Rawal…·Edward A Fisher
This paper shows that cholesterol-loaded vascular smooth muscle cells (VSMCs) lose TGFβ signaling and contractile features, but HDL-mediated cholesterol efflux restores signaling and contractile markers.