Xin Sun

A Membrane Lipid Signature Unravels the Dynamic Landscape of Group 1 ILCs

This study uses the AsGM1 membrane lipid signature to distinguish NK cells and ILC1s, capturing their plasticity across tissues and conditions.

Maternal iron deficiency impacts the placental arterial network.

The paper identifies molecular markers for placental arterial and venous endothelial cells and shows maternal iron deficiency impairs the arterial vascular network.

The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development

This study identifies agrin as a critical regulator of epicardial EMT by localizing dystroglycan to the Golgi apparatus, ensuring ECM-cytoskeletal connectivity and mechanical integrity during heart development.

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

This study shows that tissue-resident macrophages are essential for lymphatic vessel growth and patterning during heart development by remodeling the vascular plexus.

BAF chromatin remodeling complex subunit diversity promotes temporally distinct gene expression programs in cardiogenes

The paper identifies BAF complex subunit dynamics during cardiac differentiation, showing how BAF60c and BAF170 regulate gene expression programs in cardiac precursors and cardiomyocytes.

Combined use of procalcitonin and C-reactive protein levels can help clinically diagnose bacterial co-infections in children infected with H1N1 influenza

This study shows combining procalcitonin and C-reactive protein levels improves diagnosis of bacterial co-infections in children with H1N1 influenza.

Cardiac enriched BAF chromatin remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

This study shows that Baf60c regulates gene expression programs critical for heart development and function by interacting with Myocardin and controlling contractile proteins and metabolic genes.