A DNA-origami NanoTrap for studying the diffusion barriers formed by Phe-Gly-rich nucleoporins
Qi Shen, Taoran Tian, Qiancheng Xiong, Patrick D. Ellis Fisher, Yong Xiong, Thomas James Melia, C. Patrick Lusk, Chenxiang Lin
The paper introduces a DNA-origami NanoTrap to study diffusion barriers formed by FG-nups and finds that motif type, density, and arrangement are critical for barrier effectiveness.
Journal of the American Chemical Society · Jul 29, 2021Peer-reviewedSynthetic Biology