Author

Shanu Bhardwaj

Indian Institute of Technology HyderabadORCID 0000-0002-8059-0287Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Basant Kumar PateliD· 1 shared Himanshu JoshiiD· 1 shared Jessica BaaiD· 1 shared Ramkumar BalajiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Basant Kumar PatelORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintJun 17, 2026

Mechanistic Insights into Unfolding of the Mitochondrial Localization Sequence M1 of TDP-43 and Identification of a MAPKAPK2 Inhibitor as a potential binder of M1 for inhibition of TDP-43's Aberrant Mitochondrial Localization

Ramkumar Balaji, Shanu Bhardwaj, Jessica Baa…·Basant Kumar Patel

This study investigates the unfolding mechanism of TDP-43's mitochondrial localization sequence M1 and identifies a potential inhibitor, ZINC73240059, that binds M1 to block TDP-43's aberrant mitochondrial localization in ALS.

DOI 10.64898/2026.06.17.732848

humanproteomics

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