Sabyasachi Rakshit

CRTAC1-A reprograms extracellular matrix viscoelasticity to constrain glioma progression

This study identifies CRTAC1-A as a regulator of ECM viscoelasticity that suppresses glioma progression by reducing matrix stiffness and enhancing drug penetration.

Cadherin-23 Mutations Cause Calcium-Dependent, Allele-Sensitive Mechanosensory Defects

This study shows that mutations in Cadherin-23 affect tip-link function in a calcium-sensitive way, causing hearing loss without impacting balance or vision.

Titin as a mechanical damper: Balancing Stability and longevity through inter-domain linker design

The paper investigates how interdomain linkers in titin affect mechanical stability and energy retention under different force conditions, revealing a trade-off between these properties.

De-novo design of actively spinning and gyrating spherical micro-vesicles

This paper designs autonomous spherical micro-rotors using Giant Unilamellar Vesicles and enzymes to achieve spontaneous symmetry-breaking and diverse movements.