Pritam Saha

CRTAC1-A reprograms extracellular matrix viscoelasticity to constrain glioma progression

This study identifies CRTAC1-A as a regulator of ECM viscoelasticity that suppresses glioma progression by reducing matrix stiffness and enhancing drug penetration.

Cadherin-23 Mutations Cause Calcium-Dependent, Allele-Sensitive Mechanosensory Defects

This study shows that mutations in Cadherin-23 affect tip-link function in a calcium-sensitive way, causing hearing loss without impacting balance or vision.

Identification of small-molecule adjuvants that enhance the sensitivity of Escherichia coli to nitrofurantoin: Roles of Lon and MarA

This study identifies small-molecule adjuvants, specifically salicylates, that enhance nitrofurantoin's efficacy against Escherichia coli by modulating Lon protease and MarA pathways.

Titin as a mechanical damper: Balancing Stability and longevity through inter-domain linker design

The paper investigates how interdomain linkers in titin affect mechanical stability and energy retention under different force conditions, revealing a trade-off between these properties.